Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease: A meta-analysis
2024

Phytosomal Curcumin and Nonalcoholic Fatty Liver Disease

Sample size: 443 publication Evidence: moderate

Author Information

Author(s): Liu Nana, Li Hongting

Primary Institution: Chongqing College of Traditional Chinese Medicine

Hypothesis

The meta-analysis aims to study the effect of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease.

Conclusion

Phytosomal curcumin is effective to improve anthropometric indices for patients with nonalcoholic fatty liver disease.

Supporting Evidence

  • Phytosomal curcumin was associated with reduced body mass index (BMI).
  • Phytosomal curcumin significantly decreased body fat percent.
  • Phytosomal curcumin led to weight loss in patients.
  • Phytosomal curcumin reduced waist circumference.

Takeaway

Phytosomal curcumin can help people with liver problems lose weight and improve their body measurements.

Methodology

The study included a meta-analysis of randomized controlled trials comparing phytosomal curcumin with placebo.

Potential Biases

Five studies had unclear risk of performance bias due to unclear blinding.

Limitations

The analysis included only 7 RCTs, and there was significant heterogeneity in treatment duration and doses.

Participant Demographics

The included studies had a total of 443 patients with nonalcoholic fatty liver disease.

Statistical Information

P-Value

0.0003

Confidence Interval

−1.11 to −0.33

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1097/MD.0000000000040538

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication