The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
2024

The Role of Extracellular Vesicles in Psoriasis

publication Evidence: moderate

Author Information

Author(s): Tang Bin, Bi Yang, Zheng Xuwei, Yang Yujie, Huang Xiaobing, Yang Kexin, Zhong Haixin, Han Ling, Lu Chuanjian, Chen Haiming

Primary Institution: The Second Clinical College of Guangzhou University of Chinese Medicine

Hypothesis

Extracellular vesicles (EVs) may serve as biomarkers and therapeutic agents in the treatment of psoriasis.

Conclusion

Extracellular vesicles have significant potential in the development of novel therapeutic strategies for psoriasis by modulating immune responses and facilitating targeted drug delivery.

Supporting Evidence

  • Extracellular vesicles are involved in immune modulation and can serve as biomarkers for psoriasis.
  • Recent studies indicate that EVs can enhance drug delivery and therapeutic efficacy in psoriasis treatment.
  • EVs derived from mesenchymal stem cells can modulate T cell responses, potentially influencing psoriasis pathology.

Takeaway

Scientists are studying tiny particles called extracellular vesicles that can help treat psoriasis by delivering medicine and improving communication between cells.

Methodology

This review involved a systematic literature search using databases like PubMed, Embase, and Web of Science, focusing on studies related to extracellular vesicles in psoriasis.

Limitations

The review is based on existing literature and does not involve new data collection, which may limit the findings.

Digital Object Identifier (DOI)

10.3390/pharmaceutics16121586

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