The Prevalence of Previously Undiagnosed Leprosy in the General Population of Northwest Bangladesh
2008

Leprosy Prevalence in Northwest Bangladesh

Sample size: 17862 publication 10 minutes Evidence: high

Author Information

Author(s): Moet Fake J., Schuring Ron P., Pahan David, Oskam Linda, Richardus Jan Hendrik

Primary Institution: Erasmus MC, University Medical Center Rotterdam

Hypothesis

What is the prevalence of previously undiagnosed leprosy in the general population of northwest Bangladesh?

Conclusion

The prevalence of previously undiagnosed leprosy is six times higher than the registered prevalence in the area.

Supporting Evidence

  • The previously undiagnosed leprosy rate was found to be 15.1 per 10,000 individuals.
  • 27 new cases of leprosy were identified among the surveyed population.
  • The prevalence of leprosy among contacts of leprosy patients was significantly higher than in the general population.

Takeaway

In northwest Bangladesh, many people have leprosy without knowing it, and we found that it's much more common than what was previously recorded.

Methodology

Multistage cluster sampling was used to examine 20 clusters of 1,000 people each, totaling 17,862 individuals over 5 years of age.

Potential Biases

Potential selection bias on individual level as those afraid of diagnosis may avoid participation.

Limitations

Selection bias may occur as only those present during the survey were included, and some individuals may have hidden due to stigma.

Participant Demographics

The study included individuals from two districts in northwest Bangladesh, with a total population of over 4 million.

Statistical Information

P-Value

0.019

Confidence Interval

95% CI = 9.4–20.8

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000198

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