Associations between Rotating Night Shifts, Sleep Duration, and Telomere Length in Women
2011

Night Shifts, Sleep Duration, and Telomere Length in Women

Sample size: 4117 publication 10 minutes Evidence: moderate

Author Information

Author(s): Liang Geyu, Schernhammer Eva, Qi Lu, Gao Xiang, De Vivo Immaculata, Han Jiali

Primary Institution: Harvard Medical School

Hypothesis

Is there a relationship between rotating night shifts, sleep duration, and telomere length in women?

Conclusion

Sleep duration is positively associated with telomere length among women under 50 years old.

Supporting Evidence

  • Women with less than 6 hours of sleep had a 0.12 unit decrease in telomere length.
  • Significant positive association between sleep duration and telomere length was seen among women under age of 50.
  • Women with a longer history of rotating night shifts tended to have shorter telomere length.

Takeaway

Getting enough sleep is good for your body, especially for younger women, as it helps keep your cells healthy.

Methodology

The study evaluated associations using multivariable linear regression on data from the Nurses' Health Study.

Potential Biases

Potential biases include self-reported sleep duration and rotating night shifts.

Limitations

The study was limited to Caucasian women and may not generalize to other populations.

Participant Demographics

Participants were female registered nurses aged 30 to 55.

Statistical Information

P-Value

0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023462

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