Osseointegration of Anodized vs. Sandblasted Implant Surfaces in a Guided Bone Regeneration Acute Dehiscence‐Type Defect: An In Vivo Experimental Mandibular Minipig Model
2024

Comparing Anodized and Sandblasted Implant Surfaces in Bone Healing

Sample size: 15 publication 10 minutes Evidence: moderate

Author Information

Author(s): Shakeel Shahdad, Simon Rawlinson, Nahal Razaghi, Anuya Patankar, Mital Patel, Mario Roccuzzo, Thomas Gill

Primary Institution: Barts and the London School of Medicine and Dentistry, Queen Mary University of London

Hypothesis

The study aims to evaluate how different implant surface characteristics influence osseointegration and new bone formation in a guided bone regeneration model.

Conclusion

Moderately rough surfaces showed significantly better osseointegration compared to the anodized surface, despite no difference in the amount of new bone formed.

Supporting Evidence

  • At 2 and 8 weeks, newly formed bone height was similar across all groups.
  • Groups with sandblasted surfaces showed significantly higher bone-to-implant contact compared to anodized surfaces.
  • Histological analysis indicated better bone apposition for sandblasted surfaces.

Takeaway

This study looked at how different types of dental implants help bones heal. It found that some implants work better than others for helping bones grow around them.

Methodology

The study used a controlled preclinical design with a minipig model to compare three types of implant surfaces after guided bone regeneration.

Limitations

The study was conducted in a porcine model, which may not fully replicate human responses.

Participant Demographics

Fifteen female Göttingen minipigs aged 20-24 months and weighing around 40 kg were used.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 31.90–53.44

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/clr.14369

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication