Urinary Incontinence in US Adults with Diabetes Who Are Guideline-Recommended to Receive SGLT2Is: NHANES 2013–2020
2024

Urinary Incontinence in US Adults with Diabetes Recommended for SGLT2 Inhibitors

Sample size: 2366 publication Evidence: moderate

Author Information

Author(s): Lee Alexandra, Lee Sei

Primary Institution: University of California San Francisco

Hypothesis

What is the prevalence of urinary incontinence among adults with diabetes who are recommended to receive SGLT2 inhibitors?

Conclusion

Among adults with diabetes, a significant percentage of those recommended for SGLT2 inhibitors also experience frequent urinary incontinence.

Supporting Evidence

  • 14.9% of adults aged 55-59 recommended for SGLT2 inhibitors had frequent incontinence.
  • 22.7% of those recommended for SGLT2 inhibitors aged 55-59 experienced frequent incontinence.
  • 27.0% of adults aged 70+ were recommended for SGLT2 inhibitors, with 41.0% having frequent incontinence.
  • 54.6% of adults aged 55-59 were recommended for either SGLT2 inhibitors or GLP-1RAs, with 20.6% having frequent incontinence.
  • 45.1% of adults aged 70+ were recommended for either SGLT2 inhibitors or GLP-1RAs, with 34.9% having frequent incontinence.

Takeaway

Many older adults with diabetes who are supposed to take a certain medication also have a problem with leaking urine, which can be a concern for their health.

Methodology

Participants with diabetes from NHANES 2013-2020 were analyzed for guideline recommendations for SGLT2 inhibitors and reported urinary incontinence.

Potential Biases

Potential bias in self-reporting of urinary incontinence.

Limitations

The study is limited to self-reported data on urinary incontinence and may not capture all cases.

Participant Demographics

Adults aged 55-59 and 70+ with type 2 diabetes.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1455

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