GenMAPP 2: New Features and Resources for Pathway Analysis
Author Information
Author(s): Salomonis Nathan, Hanspers Kristina, Zambon Alexander C, Vranizan Karen, Lawlor Steven C, Dahlquist Kam D, Doniger Scott W, Stuart Josh, Conklin Bruce R, Pico Alexander R
Primary Institution: Gladstone Institute of Cardiovascular Disease
Conclusion
GenMAPP version 2 provides a means to rapidly interrogate complex experimental data for pathway-level changes in a diverse range of organisms.
Supporting Evidence
- GenMAPP has been widely used with over 15,000 unique user registrations and over 250 publications citing its use.
- GenMAPP version 2 includes new features to support user data import and mapping, expanded pathway resources, and increased support for different high-throughput biological assays.
- GenMAPP allows users to view and analyze genome-scale data on biological pathways, Gene Ontology terms, or any other desired grouping of genes.
Takeaway
GenMAPP is a tool that helps scientists understand complex data about genes and their interactions in biological pathways, making it easier to analyze and share this information.
Methodology
GenMAPP is implemented in Visual Basic 6.0 and is available as a stand-alone application for Windows operating systems, allowing users to organize, analyze, and share genome-scale data in the context of biological pathways.
Limitations
The pathways for non-mammalian species are mapped from human rather than the most closely related organism, and the reactions in a GenMAPP pathway are illustrations rather than computable networks.
Digital Object Identifier (DOI)
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