The tep1 gene of Sinorhizobium meliloti coding for a putative transmembrane efflux protein and N-acetyl glucosamine affect nod gene expression and nodulation of alfalfa plants
2009

The tep1 gene in Sinorhizobium meliloti and its role in nodulation of alfalfa

publication Evidence: moderate

Author Information

Author(s): van Dillewijn Pieter, Sanjuán Juan, Olivares José, Soto María José

Primary Institution: Estación Experimental del Zaidín, CSIC, Granada, Spain

Hypothesis

What is the role of the tep1 gene in swarming and symbiosis in Sinorhizobium meliloti?

Conclusion

The tep1 gene encodes a protein that helps Sinorhizobium meliloti resist chloramphenicol and influences nodulation efficiency on alfalfa plants.

Supporting Evidence

  • The tep1 mutant showed increased nodulation efficiency on alfalfa plants during the first days of interaction.
  • N-acetyl glucosamine reduced nod gene expression and nodulation efficiency when present at high concentrations.
  • The tep1 gene is linked to the efflux of compounds that influence nodulation.

Takeaway

The tep1 gene helps bacteria fight off a certain antibiotic and affects how well they can form nodules on alfalfa plants.

Methodology

The study involved creating a mutant strain of Sinorhizobium meliloti and testing its sensitivity to antibiotics and nodulation efficiency on alfalfa.

Limitations

The physiological functions of the closest SMc02161 homologs have not been experimentally tested.

Digital Object Identifier (DOI)

10.1186/1471-2180-9-17

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