Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy: a case report
2008

HIV Infection and Guillain-Barré Syndrome: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Sloan Derek J, Nicolson Andrew, Miller Alastair R O, Beeching Nick J, Beadsworth Mike B J

Primary Institution: Royal Liverpool University Hospital

Hypothesis

Can acute inflammatory demyelinating polyneuropathy present during HIV seroconversion?

Conclusion

Early HIV testing and treatment with highly active anti-retroviral therapy can lead to significant recovery in patients with unusual neurological presentations.

Supporting Evidence

  • The patient experienced rapid clinical deterioration but improved significantly after treatment.
  • Symptoms resolved within nine weeks after starting therapy.
  • Early intervention with HAART was beneficial in this case.

Takeaway

A man got very weak because of a virus called HIV, but after getting special medicine, he got better in a few weeks.

Methodology

The patient was treated with intravenous immunoglobulin and highly active anti-retroviral therapy, with clinical monitoring and neurophysiological testing.

Limitations

The case is based on a single patient, limiting generalizability.

Participant Demographics

30-year-old homosexual man.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-370

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication