Candidemia in Italy: Study of Bloodstream Infections
Author Information
Author(s): Bassetti Matteo, Taramasso Lucia, Nicco Elena, Molinari Maria Pia, Mussap Michele, Viscoli Claudio
Primary Institution: San Martino University Hospital, Italy
Hypothesis
What is the contemporary epidemiology, species distribution, antifungal susceptibility, and outcome of candidemia BSI in an Italian hospital?
Conclusion
Candidemia is a significant source of morbidity in Italy, with high mortality rates and a substantial burden of disease.
Supporting Evidence
- 348 episodes of candidemia were identified during the study period.
- 43.5% of evaluable patients died within 30 days from the onset of candidemia.
- C. parapsilosis candidemia was associated with the lowest mortality rate (36.2%).
- Patients in Internal Medicine wards had the highest mortality rate (54.1%).
Takeaway
Candidemia is a serious infection caused by yeast that can lead to death, and this study found that many patients in Italy are affected by it.
Methodology
The study enrolled all consecutive patients with candidemia from January 2008 to December 2010 and analyzed their clinical data and outcomes.
Limitations
The study is limited to a single center, which may not represent broader regional conditions.
Participant Demographics
The majority of patients had one or more comorbidities, including surgical interventions and solid tumors.
Digital Object Identifier (DOI)
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