Pleural mesothelioma and venous thrombosis: the eosinophilia link
2008

Eosinophilia and Thrombosis in Pleural Mesothelioma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Ames Paul Richard Julian, Aye Win Win

Primary Institution: Department of Haematology, West Suffolk Hospital

Hypothesis

Can peripheral blood eosinophilia contribute to the development of deep vein thrombosis in patients with pleural mesothelioma?

Conclusion

The study reports a case where reactive eosinophilia contributed to the development of deep vein thrombosis in a patient with pleural mesothelioma.

Supporting Evidence

  • Peripheral blood eosinophilia is rare in patients with pleural mesothelioma.
  • The patient developed deep vein thrombosis despite being on low molecular weight heparin prophylaxis.
  • Eosinophilia may be reactive due to factors produced by the tumor.

Takeaway

This study talks about a patient with a type of lung cancer who had a high number of eosinophils in their blood, which led to a blood clot, even though they were taking medicine to prevent it.

Methodology

Case report of a patient with pleural mesothelioma who developed peripheral blood eosinophilia and deep vein thrombosis.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

A 75-year-old male patient.

Digital Object Identifier (DOI)

10.1186/1477-9560-6-3

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