Bacteria that Kill Snails Could Help Control Schistosomiasis
Author Information
Author(s): Ardpairin Jiranun, Subkrasae Chanakan, Dumidae Abdulhakam, Pansri Supawan, Homkaew Chanatinat, Meesil Wipanee, Kumchantuek Tewarat, Phoungpetchara Ittipon, Dillman Adler R., Pavesi Coralie, Bode Helge B., Tandhavanant Sarunporn, Thanwisai Aunchalee, Vitta Apichat
Primary Institution: Naresuan University
Hypothesis
Symbiotic bacteria might be a potential molluscicide for controlling Biomphalaria glabrata.
Conclusion
Extracts from certain bacteria showed promise as effective molluscicides against Biomphalaria glabrata, which could help control schistosomiasis.
Supporting Evidence
- Five bacterial extracts showed 100% mortality in Biomphalaria glabrata snails.
- P. laumondii subsp. laumondii was the most effective with an LC50 of 54.52 µg/mL.
- Histopathological changes were observed in the snails after exposure to bacterial extracts.
- Secondary metabolites such as GameXPeptide and Rhabdopeptide were identified in the bacterial extracts.
Takeaway
Some bacteria can kill snails that spread a disease called schistosomiasis, which makes people sick. Scientists are studying these bacteria to find new ways to stop the disease.
Methodology
Bacterial isolates were identified and their extracts were tested for molluscicidal activity against Biomphalaria glabrata snails.
Limitations
The study did not evaluate the toxicity of bacterial extracts to other organisms in the environment.
Statistical Information
P-Value
p<0.001
Confidence Interval
52.47–56.61 for LC50; 87.35–91.84 for LC90
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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