Multi‐omics approach in gut and environmental microbiota research under the One Health concept
2024

Multi-omics Approach in Gut and Environmental Microbiota Research

publication Evidence: moderate

Author Information

Author(s): Kostka Anna, Gruszecka‐Kosowska Agnieszka, Ruiz‐Rodríguez Alicia, Aguilera Margarita

Primary Institution: AGH University of Krakow

Hypothesis

How does the gut microbiota composition vary among children with different body weights and what is the impact of environmental xenobiotics?

Conclusion

The study found significant differences in gut microbiota composition among normal weight, overweight, and obese children, and identified potential links between xenobiotics and health status.

Supporting Evidence

  • Significant differences in gut microbiota composition were observed across different taxonomic levels.
  • A potential relationship between xenobiotics and gut microbiota composition was identified.
  • Key geochemical factors influencing microbial diversity in groundwater samples were determined.

Takeaway

This study looks at how the tiny organisms in our gut can change based on what we eat and the environment around us, especially in kids who are different weights.

Methodology

The study used stool samples from children and groundwater samples, applying multi-omics techniques including metagenomics and chemical analysis.

Limitations

The study requires further investigation to confirm the preliminary findings and explore additional factors influencing microbiota composition.

Participant Demographics

Children of varying body weights (normal weight, overweight, obese).

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.2903/j.efsa.2024.e221104

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