Case Report: Catastrophic antiphospholipid syndrome in a pediatric patient after percutaneous treatment of aortic re-coarctation
2024

Catastrophic Antiphospholipid Syndrome in a Child After Heart Surgery

publication Evidence: moderate

Author Information

Author(s): García Herrera Iris Paola, Canales Robredo Carlos, Aboytes Zavala Magdalena, Merayo Chalico Javier, Pineda Arzate Orfanel Sebastian, Colín Ortíz José Luis, Aparicio Vera Luis Alberto

Primary Institution: Hospital Para El Niño Poblano, Puebla, Mexico

Hypothesis

The trigger for catastrophic antiphospholipid syndrome (CAPS) in this pediatric patient was vascular trauma from cardiac catheterization.

Conclusion

The patient diagnosed with catastrophic antiphospholipid syndrome after cardiac catheterization made a full recovery with appropriate treatment.

Supporting Evidence

  • The patient tested positive for antiphospholipid antibodies, confirming the diagnosis of CAPS.
  • Treatment included high doses of glucocorticoids and anticoagulation therapy.
  • One year post-diagnosis, the patient continued to test positive for antiphospholipid antibodies.

Takeaway

A girl had a serious condition called CAPS after heart surgery, but with the right treatment, she got better and is doing well now.

Methodology

The patient was treated with high doses of methylprednisolone, followed by other medications including azathioprine and enoxaparin.

Limitations

No kidney or intestinal biopsy was obtained, and the relationship between antiphospholipid antibodies and clinical evolution was not definitively established.

Participant Demographics

A 6-year-old female patient with a history of congenital heart disease.

Digital Object Identifier (DOI)

10.3389/fped.2024.1410400

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