Prognostic factors in gastric cancer with special reference to sex
1992

Prognosis of Gastric Cancer in Young Women

Sample size: 1031 publication Evidence: moderate

Author Information

Author(s): Y. Maehara, A. Watanabe, Y. Kakeji, Y. Emi, S. Moriguchi, H. Anai, K. Sugimachi

Primary Institution: Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan

Hypothesis

Is the prognosis for surgically treated gastric cancer patients poorer for women than men under age 50?

Conclusion

Women under age 50 with gastric cancer have a lower survival rate compared to men.

Supporting Evidence

  • The 10-year survival rate was 39.2% for men and 29.3% for women under age 50.
  • Statistical differences in clinicopathological factors were noted between men and women.
  • Advanced cases were more common in women, leading to lower survival rates.

Takeaway

This study found that young women with gastric cancer tend to do worse than young men, so it's important to catch the cancer early.

Methodology

Retrospective analysis of 1031 patients with advanced gastric adenocarcinoma treated between 1965 and 1983.

Potential Biases

Potential biases in patient selection and treatment protocols.

Limitations

The study is retrospective and may not account for all variables affecting survival.

Participant Demographics

689 men and 342 women, with 25.4% under age 50.

Statistical Information

P-Value

<0.01

Statistical Significance

p<0.01

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