West Nile Virus: A Newly Emergent Epidemic Disease
2001
West Nile Virus: A Newly Emergent Epidemic Disease
Sample size: 62
publication
Evidence: high
Author Information
Author(s): Vincent Deubel, Duane J. Gubler, Marcelle Layton, Mertyn Malkinson
Primary Institution: Centers for Disease Control and Prevention
Hypothesis
The study investigates the emergence and spread of West Nile virus and its impact on various species.
Conclusion
The 1999 West Nile virus outbreak in New York was linked to a virus introduced from Israel or the Middle East, highlighting the global movement of pathogens.
Supporting Evidence
- The 1999 outbreak in New York resulted in 62 cases of neurologic disease and 7 deaths.
- Virus transmission was confirmed through Culex species mosquitoes.
- Genetic analysis showed 99.9% nucleotide homology with a virus from domestic geese in Israel.
- Data suggest the virus may have persisted in Israel or been reintroduced by migrating birds.
Takeaway
West Nile virus can spread easily and cause serious illness in humans and animals, and it may have come from other countries.
Methodology
The study involved comparing virus isolates from various species and analyzing genetic sequences.
Participant Demographics
The study included humans, birds, and horses affected by the virus.
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