Emotional Dysfunction in Parkinson’s Disease
2011
Emotional Dysfunction in Parkinson’s Disease
publication
Author Information
Author(s): Lee X. Blonder, John T. Slevin
Primary Institution: University of Kentucky College of Medicine
Hypothesis
Emotional dysfunction is a significant aspect of idiopathic Parkinson's disease.
Conclusion
Emotional dysfunction, including depression and anxiety, is prevalent in Parkinson's disease and is linked to specific neurobiological pathways.
Supporting Evidence
- Depression affects 30 to 40 percent of Parkinson patients.
- Neuropsychological studies suggest abnormalities in dopaminergic pathways.
- The interaction between serotonin and dopamine systems is important for mood disorders in Parkinson's disease.
Takeaway
People with Parkinson's disease often feel sad or anxious, and this is related to changes in their brain.
Methodology
The article reviews neuropsychological and neuroimaging studies related to emotional dysfunction in Parkinson's disease.
Participant Demographics
The study discusses emotional dysfunction in Parkinson's patients, affecting 30 to 40 percent of them.
Digital Object Identifier (DOI)
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