Editorial: Single-domain antibodies—biology, engineering and emerging applications, volume II
2024

Single-domain antibodies: biology, engineering, and applications

Editorial

Author Information

Author(s): Henry Kevin A., Hussack Greg, Gettemans Jan, Brooks Cory L.

Primary Institution: Human Health Therapeutics Research Centre, National Research Council Canada

Conclusion

Single-domain antibodies (sdAbs) have evolved significantly and are now recognized as a distinct class of binding molecules with various applications in medicine.

Supporting Evidence

  • The first sdAb-based drug was approved in 2018 for treating a blood disorder.
  • sdAbs have shown effectiveness against SARS-CoV-2, especially in well-designed molecules.
  • Recent approvals of sdAb-based therapies highlight their growing importance in medicine.

Takeaway

Single-domain antibodies are special types of antibodies that are getting better and better at helping doctors find and treat diseases.

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1537054

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