Screening of medicinal plants for antibacterial principles against β-lactam resistant strains
2011
Screening of Medicinal Plants for Antibacterial Properties
Sample size: 29
publication
Evidence: moderate
Author Information
Author(s): Vinod N.V., C. Sadasivan
Primary Institution: Kannur University
Hypothesis
Can medicinal plants provide antibacterial principles against β-lactam resistant bacterial strains?
Conclusion
Certain plant extracts can enhance the effectiveness of antibiotics against resistant bacterial strains.
Supporting Evidence
- The diethyl ether extracts showed a higher degree of antimicrobial activity compared to methanol extracts.
- The extracts of H. integrifolia, P. pinnata, S. dulci, and S. samarengense enhanced the effect of amoxicillin.
- Other plant extracts did not show any noticeable synergistic effect.
Takeaway
Scientists tested 29 plants to see if they could help fight bacteria that don't respond to common antibiotics, and some plants worked well with these drugs.
Methodology
Plants were extracted using various solvents and tested for antibacterial activity using the disc diffusion method.
Limitations
Not all plant extracts showed significant synergistic effects.
Digital Object Identifier (DOI)
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