Dynamics in Cardiometabolic Risk among Turkish Adults: Similarities to that in Iranians?
2011

Dynamics in Cardiometabolic Risk among Turkish Adults

Sample size: 3687 publication Evidence: moderate

Author Information

Author(s): Onat Altan

Primary Institution: Cerrahpaşa Medical Faculty, Istanbul University

Hypothesis

The author suspects that dynamics in the development of diabetes and coronary heart disease exist in Western adults prone to impaired glucose tolerance.

Conclusion

The study highlights that low-grade systemic inflammation and oxidative stress are major determinants of cardiometabolic risk in Turkish adults, particularly affecting women.

Supporting Evidence

  • 41% of middle-aged and elderly men and 40% of women in Turkey have metabolic syndrome.
  • The prevalence of type-2 diabetes is 11% among Turks aged 35 years.
  • Low-grade systemic inflammation and oxidative stress are major determinants of cardiometabolic risk.

Takeaway

This study shows that many Turkish adults have high risks for diabetes and heart disease, especially women, due to factors like obesity and inflammation.

Methodology

The TARF study is a longitudinal population-based cohort study that followed a representative sample of Turkish adults, collecting data through questionnaires, physical exams, and blood samples.

Potential Biases

Potential bias due to the reliance on self-reported data and the specific population studied.

Limitations

The prevalence estimates of coronary heart disease are less reliable for comparison.

Participant Demographics

Participants were a random sample of Turkish adults aged 20 years or more, stratified by sex, age, geographical regions, and rural-urban distribution.

Statistical Information

Statistical Significance

p<0.05

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