(E,E)-4-{4-[3-(4-Chloroanilino)-1-hydroxybut-2-enylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl}benzenesulfonamide
2011
Study of a New Pyrazole Compound
publication
Author Information
Author(s): Asiri Abdullah M., Faidallah Hassan M., Ng Seik Weng
Primary Institution: King Abdul Aziz University
Hypothesis
The addition of a sulfamido unit to the phenyl ring is expected to improve its biological activity.
Conclusion
The study successfully synthesized a new p-sulfamylphenylpyrazole derivative.
Supporting Evidence
- The compound features a central pyrazole ring with a benzene substituent.
- The benzene ring is slightly twisted with respect to the five-membered ring.
- Intramolecular hydrogen bonds are formed by the amino and hydroxy groups.
Takeaway
Scientists made a new chemical compound that might work better in medicine by adding a special part to it.
Methodology
The compound was synthesized by heating it with 4-chloroaniline in ethanol and then recrystallizing it.
Digital Object Identifier (DOI)
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