Mammalian Sirt1: insights on its biological functions
2011
Mammalian Sirt1: Insights on Its Biological Functions
publication
Evidence: moderate
Author Information
Author(s): Rahman Shahedur, Islam Rezuanul
Primary Institution: Department of Biotechnology and Genetic Engineering, Islamic University, Kushtia -7003, Bangladesh
Conclusion
Sirt1 plays a crucial role in various biological functions, including metabolism, aging, and cancer regulation.
Supporting Evidence
- Sirt1 regulates energy homeostasis and lipid metabolism in response to nutrient availability.
- Sirt1 is involved in the regulation of obesity-associated metabolic diseases.
- Sirt1 has been shown to play a role in cancer by interacting with tumor suppressor proteins.
- Sirt1 is implicated in aging and cellular senescence.
- Sirt1 affects insulin sensitivity and may help in preventing type 2 diabetes.
Takeaway
Sirt1 is a protein that helps control how our bodies use energy and can affect aging and diseases like cancer.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website