c-Type Cytochrome-Dependent Formation of U(IV) Nanoparticles by Shewanella oneidensis
2006

Bacteria That Help Clean Up Uranium Contamination

publication Evidence: moderate

Author Information

Author(s): Matthew Marshall, James Fredrickson

Hypothesis

Can Shewanella oneidensis effectively reduce soluble uranium to insoluble uraninite using specific cytochromes?

Conclusion

The study found that the proteins MtrC and OmcA are crucial for the reduction of uranium to insoluble uraninite in Shewanella oneidensis.

Supporting Evidence

  • The mutant strain of Shewanella oneidensis could not reduce uranium, while the nonmutant could.
  • MtrC and OmcA were shown to be important for uranium reduction rates.
  • Uraninite was found to be associated with extracellular polymeric substances in nonmutant bacteria.

Takeaway

Some bacteria can help clean up toxic uranium by turning it into a form that doesn't move around in water. This study shows that certain proteins in these bacteria are really important for this process.

Methodology

The researchers used genetic and microscopy techniques to study the role of cytochromes in uranium reduction.

Limitations

More experiments are needed to fully understand the role of other agents in uranium reduction.

Digital Object Identifier (DOI)

10.1371/journal.pbio.0040282

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