Diet and Nutrition: A Spoonful of Risk?
2007

Soy Foods and Prostate Cancer Risk

Sample size: 43409 publication Evidence: moderate

Author Information

Author(s): Norie Kurahashi, Richard Hoffman

Primary Institution: Japan’s National Cancer Center

Hypothesis

Does the consumption of soy foods affect the risk of prostate cancer in Japanese men?

Conclusion

Increased consumption of soy foods is linked to a lower risk of localized prostate cancer, but miso soup consumption may increase the risk of advanced prostate cancer.

Supporting Evidence

  • Increased soy food consumption is associated with a lower risk of localized prostate cancer.
  • Consumption of miso soup is linked to a higher risk of advanced prostate cancer in men over 60.
  • Men under 60 showed increased risk for both localized and advanced prostate cancer with higher soy food consumption.

Takeaway

Eating more soy foods might help protect against some types of prostate cancer, but eating a lot of miso soup could actually increase the risk of a more serious form of the disease.

Methodology

The study analyzed diet and prostate cancer data from a cohort of Japanese men aged 45–74 who answered questions about their medical history and food consumption.

Potential Biases

Family history of prostate cancer may influence isoflavone intake and confound the association with cancer risk.

Limitations

The study did not adjust for family history of prostate cancer, which could confound the results.

Participant Demographics

Japanese men aged 45–74.

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