Potential dermal wound healing agent in Blechnum orientale Linn
2011
Wound Healing Potential of Blechnum orientale
Sample size: 24
publication
Evidence: high
Author Information
Author(s): Lai How Yee, Lim Yau Yan, Kim Kah Hwi
Primary Institution: Taylor's University, Monash University, University of Malaya
Hypothesis
The water extract of Blechnum orientale has synergistic antioxidant and antibacterial activities that promote wound healing.
Conclusion
The water extract of Blechnum orientale is a potential candidate for the treatment of dermal wounds.
Supporting Evidence
- The 2% extract-treated group showed significant reduction in wound size and faster healing compared to the control.
- Histopathological examinations revealed greater tissue regeneration in the 2% extract-treated group.
- The study validated the traditional use of Blechnum orientale for wound treatment.
Takeaway
This study found that a fern called Blechnum orientale can help heal wounds faster when used as a cream.
Methodology
The study used Sprague-Dawley rats to test the effects of different concentrations of Blechnum orientale water extract on wound healing.
Participant Demographics
Sprague-Dawley rats, 200-250 g, both sexes.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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