Prevalence of cervical neoplastic lesions and Human Papilloma Virus infection in Egypt: National Cervical Cancer Screening Project
2007

Cervical Cancer and HPV in Egypt

Sample size: 5453 publication 10 minutes Evidence: moderate

Author Information

Author(s): Howayda S Abd El All, Amany Refaat, Khadiga Dandash

Primary Institution: Suez Canal University

Hypothesis

What is the prevalence of cervical neoplastic lesions and HPV infection among Egyptian women aged 35 to 60?

Conclusion

The study found that pre-invasive high grade lesions and invasive cervical carcinoma represent 0.5% and 0.04% respectively in Egyptian women, with HPV being a significant risk factor.

Supporting Evidence

  • HPV was present in 94.3% of squamous lesions.
  • The overall predictive value of cytology was 87%.
  • Prevalence of cervical lesions was 3.04%.

Takeaway

This study looked at how many women in Egypt have early signs of cervical cancer and found that a small number have serious issues, often linked to a virus called HPV.

Methodology

A community-based cross-sectional survey was conducted, including Pap smears, biopsies, and HPV testing on women aged 35 to 60.

Potential Biases

Cultural sensitivity may have led to underreporting of sexual history and risk factors.

Limitations

The study was limited to a single period and did not follow up on cases, which may affect the understanding of trends over time.

Participant Demographics

Women aged 35 to 60, primarily from urban and rural areas in Egypt.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 1.3–3.1

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1750-9378-2-12

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