Spectrum of perforation peritonitis in Pakistan: 300 cases Eastern experience
2008

Spectrum of Perforation Peritonitis in Pakistan: 300 Cases

Sample size: 300 publication Evidence: moderate

Author Information

Author(s): Afridi Shahida Parveen, Malik Faiza, Ur-Rahman Shafiq, Shamim Shahid, Samo Khursheed A

Primary Institution: Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan

Hypothesis

The study aims to highlight the spectrum of perforation peritonitis in the East and improve its outcome.

Conclusion

The spectrum of perforation peritonitis in Pakistan differs from western countries, with a higher incidence of duodenal perforations due to acid peptic disease.

Supporting Evidence

  • The most common cause of perforation was acid peptic disease, particularly duodenal ulcers.
  • Overall mortality was recorded at 10.6%.
  • Majority of patients presented with abdominal pain and distention.

Takeaway

This study looked at 300 patients with a serious stomach problem called perforation peritonitis, finding that most had issues in the upper part of their stomach.

Methodology

A prospective study of 300 consecutive patients with perforation peritonitis was conducted over two and a half years, analyzing clinical presentations, causes, surgical treatment, complications, and mortality.

Limitations

The study excluded cases of primary peritonitis, trauma, corrosive, and postoperative peritonitis due to anastomosis leakage.

Participant Demographics

Mean age was 40.5 years, with a male to female ratio of 2.1:1.

Digital Object Identifier (DOI)

10.1186/1749-7922-3-31

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