CMR Improves Identification of Aortic Valve Morphology in Aortic Stenosis
Author Information
Author(s): Bull Sacha, Pitcher Alex, Francis Jane M, Suttie Joseph, Joseph Jubin, D'Arcy Joanna, Prendergast Bernard, Becher Harald, Karamitsos Theo D, Neubauer Stefan, Myerson Saul G
Primary Institution: Oxford University
Hypothesis
CMR is more effective than Echo in identifying aortic valve morphology in patients with aortic stenosis.
Conclusion
CMR is a more sensitive method for assessing valve morphology and determining Sievers classification in aortic stenosis than trans-thoracic echocardiography.
Supporting Evidence
- CMR identified 24 patients with bicuspid valves compared to 13 identified by Echo.
- Overall agreement between CMR and Echo was moderate with Cohen’s Kappa =0.59.
- CMR confidently assigned valve morphology classification in all 24 cases.
Takeaway
CMR is better at finding problems with heart valves than the usual ultrasound method, which missed many issues.
Methodology
65 patients underwent Echo followed by CMR to assess aortic valve morphology.
Limitations
Echo missed 46% of bicuspid valves due to limitations in visualizing valve leaflets in moderate-severe AS.
Participant Demographics
Patients with moderate-severe calcific aortic stenosis.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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