Risk factors for oral and pharyngeal cancer in women: a study from Italy and Switzerland
2000

Risk factors for oral and pharyngeal cancer in women

Sample size: 1308 publication Evidence: moderate

Author Information

Author(s): Bosetti C, Negri E, Franceschi S, Conti E, Levi F, Tomei F, Vecchia C La

Primary Institution: Istituto di Ricerche Farmacologiche ‘Mario Negri’

Hypothesis

What are the risk factors for oral and pharyngeal cancer in women from Italy and Switzerland?

Conclusion

Heavy smoking and high alcohol intake significantly increase the risk of oral and pharyngeal cancers in women.

Supporting Evidence

  • Heavy smokers had a multivariate odds ratio of 4.6 for developing oral and pharyngeal cancers.
  • High alcohol intake was associated with a multivariate odds ratio of 2.7.
  • Consumption of vegetables, fruit, β-carotene, and wholegrain foods was inversely related to cancer risk.
  • Butter and retinol were directly related to an increased risk of cancer.

Takeaway

Women who smoke a lot or drink a lot of alcohol are more likely to get mouth and throat cancer. Eating fruits and vegetables can help lower that risk.

Methodology

The study analyzed two case-control studies involving women from Italy and Switzerland.

Participant Demographics

Women from Italy and Switzerland.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.1999.0900

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