Cost-Effectiveness of Chagas Disease Vector Control Strategies in Northwestern Argentina
Author Information
Author(s): Gonzalo M. Vazquez-Prokopec, Cynthia Spillmann, Mario Zaidenberg, Uriel Kitron, Ricardo E. Gürtler
Primary Institution: Laboratorio de Eco-Epidemiología, Universidad de Buenos Aires
Hypothesis
The study aims to assess the cost-effectiveness of different vector control strategies for Chagas disease in Northwestern Argentina.
Conclusion
The mixed strategy would have averted more human cases than the fully horizontal strategy and was the most cost-effective option to interrupt parasite transmission.
Supporting Evidence
- The fully horizontal strategy showed direct cost-effectiveness ratios 1.9–3.3 times lower than other strategies.
- Community participation in vector control was essential for reducing costs.
- The prevalence of infestation decreased significantly during the attack phase of the control program.
- Villagers performed 79% of the insecticide sprays registered in Moreno.
- The cost of spraying a single house was significantly lower for the horizontal strategy compared to vertical and mixed strategies.
- The study represents the first thorough evaluation of a horizontal Chagas disease vector control program.
- Cost-effectiveness ratios were projected over a 25-year period to assess long-term effectiveness.
- The mixed strategy would have averted between 1.6 and 4.0 times more human cases than the fully horizontal strategy.
Takeaway
This study looks at how different ways to control the bugs that spread Chagas disease can save money and help more people.
Methodology
The study performed a cost-effectiveness analysis comparing fully horizontal, vertical, and mixed vector control strategies based on retrospective health records.
Potential Biases
Potential bias due to reliance on self-reported data from community leaders.
Limitations
The study did not account for opportunity costs related to villagers' time spent on control activities.
Participant Demographics
The study involved rural communities in the Moreno Department, with a population of approximately 25,000.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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