Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey
2011

Survey on Autism Treatments for Seizures

Sample size: 1023 publication 10 minutes Evidence: moderate

Author Information

Author(s): Richard E. Frye, Sreenivasula Swapna, James B. Adams

Primary Institution: University of Texas Health Science Center, Houston, USA

Hypothesis

What are the perceived effects of traditional and non-traditional treatments for seizures in children with autism spectrum disorder?

Conclusion

Parents perceive that while antiepileptic drugs improve seizure control, they may worsen other clinical factors in children with autism spectrum disorder.

Supporting Evidence

  • Parents reported that antiepileptic drugs improve seizure control but worsen other clinical factors.
  • Non-antiepileptic treatments like the ketogenic diet were perceived to improve both seizures and other clinical factors.
  • 77% of the children in the study were male, consistent with the general ASD population.

Takeaway

This study asked parents about treatments for kids with autism and seizures, finding that some medicines help with seizures but can make other problems worse.

Methodology

An online survey was conducted to gather parental perceptions on the effectiveness of various treatments for children with autism and seizures.

Potential Biases

Parents using non-traditional therapies may have biases against traditional treatments due to adverse effects.

Limitations

The study relies on parental perceptions, which may not accurately reflect clinical outcomes, and does not verify ASD diagnoses.

Participant Demographics

77% of the children were male, with a mean age of 13 years for those with clinical seizures.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1471-2431-11-37

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