Using CT Scans to Estimate Heart and Lung Fluid Levels in Critically Ill Patients
Author Information
Author(s): Bernd Saugel, Konstantin Holzapfel, Jens Stollfuss, Tibor Schuster, Veit Phillip, Caroline Schultheiss, Roland M Schmid, Wolfgang Huber
Primary Institution: Klinikum rechts der Isar der Technischen Universität München
Hypothesis
Can CT-based estimation of cardiac preload and pulmonary hydration accurately assess volume status in critically ill patients?
Conclusion
CT-based estimation of GEDVI and EVLWI is not accurate for predicting cardiac preload and extravascular lung water in critically ill patients compared to invasive TPTD assessment.
Supporting Evidence
- CT-based estimations showed significant differences from TPTD measurements.
- Accuracy of CT estimation for GEDVI was low, with sensitivity for low GEDVI at 0%.
- CT estimation of EVLWI also demonstrated low accuracy and sensitivity.
Takeaway
Doctors used CT scans to check how much fluid is in the heart and lungs of very sick patients, but the scans didn't work well compared to other methods.
Methodology
Retrospective analysis of 30 ICU patients comparing CT-based estimations of GEDVI and EVLWI with TPTD measurements.
Potential Biases
Radiologists were blinded to clinical data, which may have affected estimations.
Limitations
The study was monocentric, retrospective, and had a time interval between TPTD and CT scans.
Participant Demographics
{"sex":{"female":14,"male":16},"age":{"median":66,"range":"27-83"},"height":{"median":170,"range":"150-180"},"weight":{"median":68,"range":"44-112"}}
Statistical Information
P-Value
p<0.001
Confidence Interval
{"GEDVI":"95% CI: +0.00 to +0.38","EVLWI":"95% CI: -0.20 to +0.13"}
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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