Hyperbaric Oxygen Therapy Combined With Standard Wound Care Versus Standard Wound Care Alone in Patients With Diabetic Foot Ulcers: A Prospective Comparative Study
2024

Hyperbaric Oxygen Therapy for Diabetic Foot Ulcers

Sample size: 60 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Myrthong Aldrin L, Gurav Shrutika, Mahankudo Suresh, Ansari Kashif F, Sawant Manasi, Lahoti Kaushal

Primary Institution: Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Mumbai, IND

Hypothesis

Does adjuvant hyperbaric oxygen therapy (HBOT) combined with standard wound care (SWC) improve healing in patients with diabetic foot ulcers compared to SWC alone?

Conclusion

Adjuvant HBOT and SWC are more effective than SWC alone in healing diabetic foot ulcers and reducing minor amputations.

Supporting Evidence

  • Both groups showed significant reduction in pain score, wound size, and inflammation at four weeks.
  • The HBOT group had a greater proportion of healthy granulation tissue compared to the SWC group.
  • Adjuvant HBOT led to a significantly reduced incidence of minor amputation.

Takeaway

This study found that using hyperbaric oxygen therapy along with regular wound care helps heal foot wounds in diabetes patients better than just using regular care.

Methodology

This was a prospective, randomized, controlled study involving 60 adult patients with diabetic foot ulcers, divided into two groups receiving either HBOT with SWC or SWC alone.

Limitations

The sample size was relatively small, the follow-up duration was short, and the study was conducted at a single center.

Participant Demographics

Adult patients aged 18 years or more with non-healing diabetic foot ulcers.

Statistical Information

P-Value

p=0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.7759/cureus.74964

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