Anti-Mullerian hormone levels decline under hormonal suppression: a prospective analysis in fertile women after delivery
2011

AMH Levels Decline After Delivery in Fertile Women

Sample size: 210 publication Evidence: moderate

Author Information

Author(s): Weghofer Andrea, Dietrich Wolf, Ortner Iris, Bieglmayer Christian, Barad David, Gleicher Norbert

Primary Institution: Medical University Vienna, Austria

Hypothesis

This study aims to determine age-specific ranges of AMH in women with proven fertility.

Conclusion

Fertile women show declining AMH levels with age, which are lower than those in infertile women.

Supporting Evidence

  • AMH levels declined with advancing female age from 0.9-1.1 to 0.6-0.9 and 0.2-0.4 ng/mL.
  • AMH levels were lower than reported in the literature for infertile patients.
  • The study found no significant association between AMH levels and the resumption of menses.

Takeaway

As women get older, their AMH levels go down, even if they are fertile, and these levels are lower than those found in women who have trouble getting pregnant.

Methodology

210 fertile women aged 18-40 were recruited for AMH measurements within 14 days after delivery, stratified into three age groups.

Limitations

The study only included women with proven fertility, which may not reflect the general population.

Participant Demographics

Women aged 18-40 years, with spontaneous conception within six months.

Statistical Information

P-Value

<0.001

Confidence Interval

95% CI, 0.5-0.7

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1477-7827-9-98

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