Osteoporosis Risk Factors After Gastrectomy for Gastric Cancer
Author Information
Author(s): Lee Hyun-Jae, Ahn Hye Seong, Han Dong-Seok
Primary Institution: Seoul National University Hospital
Hypothesis
What are the perioperative risk factors for osteoporosis after radical gastrectomy for gastric cancer?
Conclusion
Osteoporosis was diagnosed in 38.1% of patients after radical gastrectomy, with age, body weight, sex, serum calcium, creatinine, and alkaline phosphatase being significant risk factors.
Supporting Evidence
- 72 out of 189 patients were diagnosed with osteoporosis post-surgery.
- Osteoporosis rates peaked at 36 months after surgery.
- Calcium and vitamin D supplements were prescribed to 83.1% of patients.
Takeaway
After stomach surgery for cancer, many patients can get weak bones, especially older people and women. Doctors need to check for this problem early.
Methodology
This retrospective cohort study analyzed patients who underwent dual-energy X-ray absorptiometry after gastrectomy for gastric cancer from 2016 to 2019.
Potential Biases
Selection bias may have occurred due to the single-institution study design.
Limitations
The study was retrospective, had a small sample size, and did not account for all potential factors affecting osteoporosis.
Participant Demographics
{"mean_age":65.5,"sex_distribution":{"male":66.1,"female":33.9},"high_income_group":89.9,"low_income_group":10.1}
Statistical Information
Confidence Interval
{"age":"1.020–1.098","body_weight":"0.914–0.987","sex":"1.138–4.739","serum_ALP":"1.006–1.040","serum_Ca":"0.130–0.980","serum_Cr":"0.002–0.268","ALP_postop":"1.003–1.030"}
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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