Angiolymphoid hyperplasia with eosinophilia: efficacy of isotretinoin?
2006

Isotretinoin for Angiolymphoid Hyperplasia with Eosinophilia

Sample size: 1 publication Evidence: low

Author Information

Author(s): El Sayed Fouad, Dhaybi Rola, Ammoury Alfred, Chababi Myrna

Primary Institution: Division of Dermatology, Faculty of Medicine, Lebanese University, Beirut, Lebanon

Hypothesis

Can isotretinoin effectively treat angiolymphoid hyperplasia with eosinophilia?

Conclusion

Isotretinoin may help treat angiolymphoid hyperplasia with eosinophilia by reducing certain growth factors.

Supporting Evidence

  • Isotretinoin led to complete resolution of one scalp nodule.
  • The remaining nodules decreased in size but did not resolve.
  • Liver function tests and lipid profiles remained normal during treatment.

Takeaway

A man with a skin condition had one of his nodules go away after taking a medicine called isotretinoin for a year, but the other nodules didn't disappear.

Methodology

The patient was treated with isotretinoin (0.5 mg/kg/day) for one year, and lesions were monitored for changes.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

32-year-old white male.

Digital Object Identifier (DOI)

10.1186/1746-160X-2-32

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