Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine cervical cancers
1999
Role of PD-ECGF in Uterine Cervical Cancers
publication
Author Information
Author(s): Fujimoto J, Sakaguchi H, Hirose R, Ichigo S, Tamaya T
Primary Institution: Gifu University School of Medicine
Hypothesis
High levels of PD-ECGF in uterine cervical cancers are associated with worse patient prognosis.
Conclusion
Patients with high PD-ECGF expression in uterine cervical cancers have a worse prognosis compared to those with low expression.
Supporting Evidence
- High PD-ECGF expression correlates with worse prognosis in cervical cancer patients.
- PD-ECGF is highly expressed in squamous cell carcinoma of the cervix.
- PD-ECGF may contribute to tumor growth through angiogenesis.
Takeaway
This study found that a protein called PD-ECGF helps tumors grow in cervical cancer, and having more of it means the cancer is likely to be worse.
Digital Object Identifier (DOI)
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