Diffuse Alveolar Damage: A Common Phenomenon in Progressive Interstitial Lung Disorders
2011
Diffuse Alveolar Damage in Lung Diseases
publication
Evidence: moderate
Author Information
Author(s): Kaarteenaho Riitta, Kinnula Vuokko L.
Primary Institution: Oulu University Hospital, University of Oulu; Helsinki University Hospital, University of Helsinki
Hypothesis
Understanding the mechanisms underlying diffuse alveolar damage (DAD) is crucial for improving treatment of interstitial lung diseases.
Conclusion
Diffuse alveolar damage is a common and serious feature in various interstitial lung diseases, often leading to poor prognosis.
Supporting Evidence
- DAD is associated with high mortality in patients with interstitial lung diseases.
- Acute exacerbations of idiopathic pulmonary fibrosis often involve DAD.
- Viral infections can lead to DAD in the lungs.
Takeaway
Diffuse alveolar damage is like a big problem in the lungs that can happen in many different lung diseases, making it hard for people to breathe.
Limitations
The rarity of DAD-associated lung diseases makes it difficult to gather large patient samples for study.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website