Reply: K-Ras: a prognostic factor for survival in non-small cell lung cancer
2006
K-Ras as a Prognostic Factor in Lung Cancer
publication
Evidence: moderate
Author Information
Author(s): C. Mascaux
Primary Institution: Institut Jules Bordet
Hypothesis
Is K-Ras a prognostic factor for survival in non-small cell lung cancer?
Conclusion
K-Ras is a potential prognostic factor for survival in lung cancer according to the literature published until the end of 2003.
Supporting Evidence
- K-Ras was discussed in the context of its controversial results in the literature.
- The authors highlighted the need for meta-analyses to clarify the role of K-Ras.
- Some studies cited were excluded from the systematic review for not meeting criteria.
Takeaway
K-Ras might help doctors understand how long someone with lung cancer might live, based on past studies.
Methodology
The authors conducted a systematic review and meta-analysis of existing studies on K-Ras and its prognostic role in lung cancer.
Limitations
The predictive role of K-Ras for chemotherapy response and its impact on survival after chemotherapy were not included in the meta-analysis.
Digital Object Identifier (DOI)
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