Genetic testing of newborns for type 1 diabetes susceptibility: a prospective cohort study on effects on maternal mental health
2010

Impact of Genetic Testing for Type 1 Diabetes on Mothers' Mental Health

Sample size: 7390 publication 10 minutes Evidence: high

Author Information

Author(s): Aas Kaja K, Tambs Kristian, Kise Marit S, Magnus Per, Rønningen Kjersti S

Primary Institution: Norwegian Institute of Public Health

Hypothesis

Does receiving genetic risk information about their newborns negatively affect maternal mental health?

Conclusion

The study found no evidence that genetic risk information about newborns negatively impacts the mental health of mothers.

Supporting Evidence

  • 166 mothers received information about high genetic risk for type 1 diabetes.
  • 7224 mothers were informed their child did not have a high-risk genotype.
  • Maternal mental health was assessed before and after receiving genetic risk information.
  • Results showed no significant changes in anxiety, depression, self-esteem, or life satisfaction.

Takeaway

The study looked at whether telling mothers their babies might get diabetes made them feel worse. It found that it didn't change how the mothers felt.

Methodology

The study used questionnaire data from the Norwegian Mother and Child Cohort (MoBa) study, comparing mental health measures before and after mothers received genetic risk information.

Potential Biases

Self-selection bias may have occurred as participants chose to receive genetic testing.

Limitations

The time lag between receiving risk information and mental health assessment may have affected results.

Participant Demographics

Mothers included in the study delivered between 2001 and 2006, with a majority in 2005; the sample consisted of 166 mothers with high-risk children and 7224 with non-high-risk children.

Statistical Information

P-Value

p = 0.9

Confidence Interval

95% CI 0.64-1.48

Statistical Significance

p = 0.9

Digital Object Identifier (DOI)

10.1186/1471-2350-11-112

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication