Potential Benefits from Physical Exercise in Advanced Cancer Patients Undergoing Systemic Therapy? A Narrative Review of the Randomized Clinical Trials
2024

Benefits of Exercise for Cancer Patients

Sample size: 1874 publication Evidence: moderate

Author Information

Author(s): Bozzetti Federico

Primary Institution: Residenza Querce, Milanodue, Italy

Hypothesis

Can physical exercise improve outcomes for advanced cancer patients undergoing systemic therapy?

Conclusion

Physical exercise may enhance physical function and quality of life in advanced cancer patients undergoing chemotherapy.

Supporting Evidence

  • Compliance with physical exercise was reported in about 70% of the studies.
  • 61% of studies showed benefits in physical function for non-malnourished patients.
  • 100% of studies showed benefits in quality of life for malnourished patients.

Takeaway

Exercise can help cancer patients feel better and stronger, even when they're getting treatment.

Methodology

The review analyzed 35 randomized controlled trials comparing physical exercise to usual care in advanced cancer patients receiving chemotherapy.

Potential Biases

Self-reported adherence to exercise may be overestimated compared to objective measures.

Limitations

The review included a heterogeneous patient population and did not perform formal statistical analysis due to variability in study designs.

Participant Demographics

Patients included both malnourished and well-nourished individuals, with a median age of 63 years.

Digital Object Identifier (DOI)

10.3390/curroncol31120563

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