Use of Hormone Blockers in Transgender Teenagers: A Scoping Review
2024

Use of Hormone Blockers in Transgender Teenagers: A Scoping Review

Sample size: 6 publication Evidence: moderate

Author Information

Author(s): Herrera Jerez M. J., Castro-Peraza M. E., Delgado Morales N. M., Arias Rodriguez A.

Primary Institution: University of La Laguna

Hypothesis

Could the use of hormone blockers have a positive effect on mental health?

Conclusion

The use of hormone blockers in transgender adolescents can be beneficial, as a reduction in mental health issues was observed during and after their use.

Supporting Evidence

  • The use of hormone blockers can alleviate distress in trans minors, providing time to weigh different options.
  • Access to puberty suppression during adolescence was associated with a reduction in lifetime suicide rates among transgender adults.
  • Improvements in mental health outcomes, including reductions in depression, anxiety, and suicidal ideation, were observed.
  • Most adolescents (93%) who use GnRHa later begin with gender-affirming hormone therapy.

Takeaway

This study looks at how hormone blockers can help transgender teens feel better mentally. They can make it easier for them to deal with their feelings about their bodies.

Methodology

A scoping review was conducted to explore the impact of hormone blockers on the mental health of transgender youth and how diagnostic criteria influence access to these treatments.

Potential Biases

Cultural and healthcare system differences likely influence treatment applicability, suggesting the need for localized studies.

Limitations

The review did not find conclusive data on the use of hormone blockers in transgender adolescents, and the lack of longitudinal data remains a gap in the literature.

Participant Demographics

The studies included transgender adolescents, with a focus on those diagnosed with gender dysphoria.

Digital Object Identifier (DOI)

10.3390/nursrep14040299

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