Cardiac Complications in Patients with Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Observational Studies
2011

Cardiac Complications in Patients with Community-Acquired Pneumonia

Sample size: 12168 publication Evidence: moderate

Author Information

Author(s): Vicente Corrales-Medina, Kathryn N. Suh, Gregory Rose, Julio A. Chirinos, Steve Doucette, William D. Cameron, Dean A. Fergusson

Primary Institution: University of Ottawa

Hypothesis

What is the incidence of major cardiac complications in patients with community-acquired pneumonia (CAP)?

Conclusion

Major cardiac complications occur in a substantial proportion of patients with CAP, especially in those requiring hospitalization.

Supporting Evidence

  • Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality.
  • Acute cardiac events can be triggered by CAP.
  • The pooled incidence rates for overall cardiac complications in hospitalized CAP patients was 17.7%.

Takeaway

When people get pneumonia, it can cause serious heart problems, especially in older patients. Doctors need to be aware of this to help treat patients better.

Methodology

The study involved a systematic review and meta-analysis of observational studies that reported cardiac complications in patients with CAP.

Potential Biases

Potential bias in the ascertainment and reporting of cardiac events due to the lack of definitions and methodological rigor in some studies.

Limitations

The study is limited by the small number of studies focusing on cardiac outcomes and the lack of clear definitions for cardiac complications in many studies.

Participant Demographics

The study primarily included immunocompetent adults with clinical and radiological evidence of CAP.

Statistical Information

Confidence Interval

CI 13.9–22.2

Digital Object Identifier (DOI)

10.1371/journal.pmed.1001048

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