The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II
2011

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II

publication Evidence: moderate

Author Information

Author(s): Aristo Vojdani, Jama Lambert

Primary Institution: Immunosciences Lab., Inc., Los Angeles, CA, USA

Hypothesis

The study investigates the role of Th17 cells and IL-17 in neuroimmune disorders and how CAM therapies can target these pathways.

Conclusion

The study suggests that targeting IL-17 activity through CAM therapies may help restore the integrity of the intestinal and blood-brain barriers in patients with neuroinflammation.

Supporting Evidence

  • Th17 cells produce IL-17, which contributes to inflammation and blood-brain barrier breakdown.
  • Environmental stressors can disrupt gut function, leading to neuroinflammation.
  • Targeting IL-17 may help in designing effective CAM therapies for neuroimmune disorders.

Takeaway

This study looks at how certain immune cells can cause problems in the brain and gut, and how special treatments can help fix these issues.

Methodology

The article reviews existing research on Th17 cells, IL-17, and their effects on neuroinflammation and gut barrier function.

Digital Object Identifier (DOI)

10.1093/ecam/nep063

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