PREDICTING ALL-CAUSE MORTALITY USING THE SARCOPENIA PHENOTYPE: EVIDENCE FROM THE KFACS
2024

Predicting All-Cause Mortality Using the Sarcopenia Phenotype

Sample size: 2400 publication Evidence: moderate

Author Information

Author(s): Kim Miji, Shin Hyung Eun, Lee Daehyun, Jung Heeeun, Jang Jae Young, Cho Hyunjin, Lim Nahyun, Won Chang Won

Primary Institution: Kyung Hee University

Hypothesis

The study investigates the association between sarcopenia phenotypes and all-cause mortality.

Conclusion

Sarcopenia, defined by reduced muscle mass and strength, is linked to higher mortality rates in older adults.

Supporting Evidence

  • The prevalence of sarcopenia was 15.4% in men and 7.5% in women.
  • 203 deaths occurred during the study.
  • 6-year mortality rates were higher in individuals with sarcopenia.

Takeaway

Older people with less muscle and strength are more likely to die sooner than those with more muscle and strength.

Methodology

The study used a prospective 6-year follow-up analysis and discrete-time Cox proportional hazards models.

Participant Demographics

52.8% women; mean age 76.0±3.9 years.

Statistical Information

P-Value

0.06

Confidence Interval

95% CI: 1.9–2.5

Statistical Significance

p=0.06

Digital Object Identifier (DOI)

10.1093/geroni/igae098.4048

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