Time-restricted eating to address persistent cancer-related fatigue among cancer survivors: A randomized controlled trial
2024

Time-Restricted Eating to Reduce Cancer-Related Fatigue

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kleckner Amber S., Clingan Carin L., Youngblood Shari M., Kleckner Ian R., Quick Lauren, Elrod Rebecca D., Zhu Shijun, Manoogian Emily N. C., Panda Satchidananda, Badros Ashraf Z., Emadi Ashkan

Primary Institution: University of Maryland School of Nursing

Hypothesis

Can time-restricted eating reduce cancer-related fatigue in survivors?

Conclusion

A 12-week time-restricted eating program led to less fatigue in cancer survivors compared to a control group.

Supporting Evidence

  • Participants in the TRE group reported a significant reduction in fatigue scores.
  • The TRE group showed a clinically meaningful improvement in fatigue compared to the control group.
  • Glucose levels tended to be lower in the TRE group, indicating potential metabolic benefits.
  • Adherence to the TRE protocol was monitored through food logs and wearable devices.

Takeaway

Eating only during a specific 10-hour window each day can help cancer survivors feel less tired.

Methodology

Participants were randomized to either a time-restricted eating group or a control group, receiving nutrition counseling and logging their eating habits over 12 weeks.

Potential Biases

Potential bias due to self-reported data and the small sample size.

Limitations

High dropout rate before randomization and a small sample size limit the generalizability of the findings.

Participant Demographics

77% female, 53% Black/African American, 43% White, 7% Hispanic; average age 54.1 years.

Statistical Information

P-Value

0.11

Statistical Significance

p=0.11

Digital Object Identifier (DOI)

10.21203/rs.3.rs-5530166

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