Distribution and Determinants of Long-Acting Injectable Antipsychotic Medication Use Among Older Adults
2024

Use of Long-Acting Injectable Antipsychotics in Older Adults

Sample size: 8481 publication Evidence: moderate

Author Information

Author(s): Lohman Matthew, Verma Mansi, Jones Paige, Scott Victoria, Fields Eve

Primary Institution: University of South Carolina

Hypothesis

What factors influence the use of long-acting injectable antipsychotic medications among older adults?

Conclusion

LAI use among older adults varies significantly based on sociodemographic characteristics.

Supporting Evidence

  • 1,400 adults age > 60 used LAIs in 2022.
  • Older adults were less likely to use LAIs compared to younger adults.
  • Older adults were more likely to use first-generation LAIs than second-generation LAIs.

Takeaway

Older people use long-acting antipsychotic medications differently based on their age, race, and where they live.

Methodology

Analysis of electronic health records and logistic regression models.

Potential Biases

Potential bias in the sample due to geographic and demographic limitations.

Limitations

The study is limited to patients receiving services at specific mental health centers in South Carolina.

Participant Demographics

Patients aged > 60, with a focus on race/ethnicity, gender, and geographic location.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0518

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