2-Chloro-1-[4-(2-fluorobenzyl)piperazin-1-yl]ethanone
2011
Study of 2-Chloro-1-[4-(2-fluorobenzyl)piperazin-1-yl]ethanone
publication
Evidence: moderate
Author Information
Author(s): Zhang Cunlong, Zhai Xin, Wan Furen, Gong Ping, Jiang Yuyang
Primary Institution: Shenyang Pharmaceutical University
Conclusion
The study successfully synthesized and characterized the title compound, revealing its molecular structure and conformation.
Supporting Evidence
- The piperazine ring adopts a chair conformation.
- The dihedral angles between the rings and planes were measured.
- The synthesis yielded a pure compound with a 90% yield.
Takeaway
The researchers made a new chemical compound and looked at its structure to understand how it is shaped.
Methodology
The compound was synthesized using chloroacetic chloride and 1-(2-fluorobenzyl)piperazine, followed by characterization through X-ray crystallography.
Digital Object Identifier (DOI)
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