Biomarker Validation of Dietary Intervention in Two Multiethnic Populations
2006

Dietary Intervention and Nutrient Levels in Multiethnic Populations

Sample size: 209 publication 10 minutes Evidence: moderate

Author Information

Author(s): Eliassen A. Heather, Colditz Graham A, Peterson Karen E, Furtado Jeremy D, Fay Martha E, Sorensen Glorian, Emmons Karen M

Primary Institution: Harvard Medical School

Hypothesis

Does dietary intervention affect plasma nutrient concentrations in multiethnic populations?

Conclusion

The study found significant differences in plasma nutrient concentrations between intervention and usual care groups, indicating the intervention's impact on dietary intake.

Supporting Evidence

  • Participants in the intervention group had higher plasma concentrations of retinol and α-carotene.
  • Self-reported multivitamin users had significantly higher concentrations of several nutrients.
  • Those consuming more fruits and vegetables had higher levels of lutein and zeaxanthin.

Takeaway

This study looked at how changing diets can affect the nutrients in our blood, showing that people who followed the diet had better nutrient levels.

Methodology

Participants completed questionnaires and provided blood samples to measure plasma nutrient concentrations.

Potential Biases

Self-reported dietary changes may reflect intervention-related bias rather than actual changes.

Limitations

The study only collected postintervention blood samples, preventing assessment of changes from preintervention to postintervention.

Participant Demographics

Participants had a mean age of 47.7 years, 49% were female, and 69% were white.

Statistical Information

P-Value

P = .01 for retinol, P = .03 for α-carotene

Statistical Significance

p<0.05

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication