How do patient-reported outcome measures affect treatment intensification and patient satisfaction in the management of psoriatic arthritis? A cross sectional study of 503 patients
2024

Impact of Patient-Reported Outcomes on Psoriatic Arthritis Treatment Decisions

Sample size: 503 publication 10 minutes Evidence: moderate

Author Information

Author(s): Coyle Conor, Watson Lily, Whately-Smith Caroline, Brooke Mel, Kiltz Uta, Lubrano Ennio, Queiro Ruben, Trigos David, Brandt-Juergens Jan, Choy Ernest, D’Angelo Salvatore, Delle Sedie Andrea, Dernis Emmanuelle, Wirth Théo, Guis Sandrine, Helliwell Philip, Ho Pauline, Hueber Axel, Joven Beatriz, Koehm Michaela, Morales Carlos Montilla, Packham Jon, Pinto Tasende Jose Antonio, Ramírez Julio, Ruyssen-Witrand Adeline, Scrivo Rossana, Twigg Sarah, Welcker Martin, Soubrier Martin, Gossec Laure, Coates Laura C

Primary Institution: Oxford University Hospitals

Hypothesis

Does the PsA Impact of Disease questionnaire (PsAID-12) influence treatment intensification and patient satisfaction in psoriatic arthritis management?

Conclusion

The study found that while PsAID-12 scores correlate with treatment escalation, most clinicians reported that it did not significantly influence their treatment decisions.

Supporting Evidence

  • 36.2% of patients had changes made to treatment, with 88.8% of those experiencing treatment escalation.
  • The mean PsAID-12 score was higher for patients with treatment escalation.
  • Physician's assessment of disease activity had the most statistically significant effect on treatment escalation.
  • Treatment escalation was more likely in patients not treated with biologic therapies.
  • Patient-reported outcomes were generally high, indicating satisfaction with consultations.

Takeaway

Doctors look at many things when deciding how to treat patients with psoriatic arthritis, but the patients' own reports about their condition don't always change what the doctors decide.

Methodology

The study was a cross-sectional analysis of adult patients with psoriatic arthritis who completed the PsAID-12 questionnaire before their rheumatology appointments.

Potential Biases

Potential bias due to the selection of patients from specialized clinics and the subjective nature of patient-reported outcomes.

Limitations

The study was conducted in specialist clinics, which may not reflect the broader population of patients with psoriatic arthritis.

Participant Demographics

49.1% female, mean age 53 years, median age 55 years.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI for treatment escalation percentage

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1093/rheumatology/kead679

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